Fluphenazine Hydrochloride BP and Nortriptyline Hydrochloride combination is an effective preparation for the patients suffering from anxiety or depression or both. Fluphenazine is a tranquilizer of the phenothiazine type. Nortriptyline is a tricyclic antidepressant having less sedative action. This combination helps to restore functional ability without developing any drug dependence. Apresin® is indicated for the treatment of mild to moderate mixed anxiety/depression, emotional disturbance, sleep disorder and also in gastric problems.