Prelica® 50

Prelica® 50

Prelica® is a structural derivative of the inhibitory neurotransmitter gamma-amino butyric acid (GABA). Prelica is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, management of post herpetic neuralgia, partial onset seizures, management of fibromyalgia.

Prelica® does not bind directly to GABA A, GABA B, or benzodiazepine receptor. It is inactive at serotonin and dopamine receptors and does not inhibit dopamine, serotonin, or noradrenaline reuptake. Prelica® binds with high affinity to the alpha 2 -delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Prelica® oral bioavailability is equal or more than 90% and is independent of dose. It is eliminated from the systemic circulation primarily by renal excretion as unchanged drug with a mean elimination half-life of 6.3 hours in subjects with normal renal function.

Presentation:

Prelica® 25 : Each capsule contains Pregabalin INN 25 mg.
Prelica® 50 : Each capsule contains Pregabalin INN 50 mg.
Prelica® 75 : Each capsule contains Pregabalin INN 75 mg.

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